This is a Macintosh executable version of Clustal W, the multiple 
biosequence aligment program.  Two versions of Clustal W for Mac are
provided, "clustalwFAT" and "clustalw-big'n'FAT".  Both of these
are "fat" binaries that include native PowerPC code as well as Motorola 68K
code, and will run optimally on either regular Macs or newer PowerMacs.

The program clustalwFAT needs about 700 kb of memory to run.  It is compiled 
with the following maximum values:

#define MAXLEN      1000   /* Max Sequence Length */
#define MAXN        30     /* Max Number of Sequences */
#define FSIZE       5000   /* Work space for pairwise alignments */
#define MAXTREE     1000   /* Max Nodes for phylogenetic tree */


The program clustalw-big'n'FAT needs 8000 kb of memory to run.  It is compiled 
with the following maximum values:

#define MAXLEN      7000   /* Max Sequence Length */
#define MAXN        500    /* Max Number of Sequences */
#define FSIZE       25000   /* Work space for pairwise alignments */
#define MAXTREE     5000   /* Max Nodes for phylogenetic tree */


Note -- The apps start up with a dialog asking if you have "command-line" parameters
to enter.  Don't enter any, just okay this and go on to where you are 
prompted for inputs.

These were compiled using MetroWerks' CodeWarrior version 4 for PowerPC and 68K.

Compiled by d.g.gilbert, October 94.

------------------------------------------
README for Clustal W version 1.4  September 1994


Julie Thompson (Thompson@EMBL-Heidelberg.DE)
Toby Gibson    (Gibson@EMBL-Heidelberg.DE)

European Molecular Biology Laboratory
Meyerhofstrasse 1
D 69117 Heidelberg
Germany


Des Higgins (Higgins@EBI.AC.UK)

European Bioinformatics Institute
Hinxton Hall
Hinxton
Cambridge CB10 1RQ
UK


Please e-mail bug reports/complaints/suggestions (polite if possible)
to Toby Gibson or Des Higgins.  

------------------------------------------
Programmer notes for ClustalwFAT changes for Mac version (dgg) :

clustalw.c:

old>>>>
    #ifdef THINK_C 

new>>>>>
    #if defined( THINK_C) || defined(__MWERKS__)


clustalw.h
    /*#define VMS 1                 VAX or ALPHA VMS */
new>>>>>>
    #define BIGMAC 1     /*        Large problems,  Metrowerks OR Think_C for MacIntosh */
      /* #define MAC 1              Think_C for MacIntosh */
<<<<<<<new
    
new>>>>>>
    #elif BIGMAC
    #define MAC 1
    #define DIRDELIM ':'
    #define MAXLEN    7000
    #define MAXN    500
    #define FSIZE       25000
    #define MAXTREE   5000
    #define LINELENGTH      60
    #define GCG_LINELENGTH  50
<<<<<<new
    #elif MAC
    


general.h:

    #ifdef THINK_C
    
    #define const         /* THINK C doesn't know about these identifiers */
    #define signed
    #define volatile
    #define int long
    #define Boolean int
    #define pint short      /* cast ints in printf statements as pint */
new>>>>>>>>>>>>>  
    #elif defined(__MWERKS__)
    
    #define pint short      /* cast ints in printf statements as pint */
<<<<<<<<<<<<<<new 
    #else               /* not Macintoshs */